XPC antibody [C2C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX102840
Zusätzliche Namen:: XPC complex subunit, DNA damage recognition and repair factor , RAD4 , XP3 , XPCC , p125
Anwendung:: WB, IHC-P
Konzentration:: 0.16 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human XPC. The exact sequence is proprietary.
Klon:: C2C3
Uniprot:: Q01831
Synonyme:: DNA repair protein complementing XP-C cells;mutant xeroderma pigmentosum group C;p125;RAD4;Xeroderma pigmentosum group C-complementing protein;xeroderma pigmentosum, complementation group C;XP3;XPCC
Weitere Details:: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Versandbedingungen:: Blue Ice