GTX102731
IL10 Receptor alpha antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX102731
- Zusätzliche Namen:
- interleukin 10 receptor subunit alpha , CD210 , CD210a , CDW210A , HIL-10R , IL-10R1 , IL10R
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1.68 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the Intracellular domain of human IL10 Receptor alpha. The exact sequence is proprietary.
- Uniprot:
- Q13651
- Synonyme:
- CD210;CD210a;CDW210A;HIL-10R;IL-10 receptor subunit alpha;IL-10R subunit 1;IL-10R subunit alpha;IL-10R1;IL-10RA;IL10R;interleukin 10 receptor, alpha;interleukin-10 receptor alpha chain;interleukin-10 receptor subunit 1;interleukin-10 receptor subunit alpha
- Weitere Details:
- The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice