Grp78 antibody [N2C1], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX102580
Zusätzliche Namen:: heat shock protein family A (Hsp70) member 5 , BIP , GRP78 , HEL-S-89n , MIF2
Anwendung:: WB, IHC-P, IF, ICC, IP
Konzentration:: 1.28 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Fish, Human, Mouse, Rat, Insect/Arthropod
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human Grp78. The exact sequence is proprietary.
Klon:: N2C1
Uniprot:: P11021
Synonyme:: 78 kDa glucose-regulated protein;binding-immunoglobulin protein;BIP;endoplasmic reticulum chaperone BiP;endoplasmic reticulum lumenal Ca(2+)-binding protein grp78;epididymis secretory sperm binding protein Li 89n;glucose-regulated protein, 78kDa;GRP78;heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa);heat shock protein 70 family protein 5;heat shock protein family A member 5;HEL-S-89n;HSP70 family protein 5;immunoglobulin heavy chain-binding protein
Weitere Details:: When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]

Versandbedingungen:: Blue Ice