TMS1 antibody [N1C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX102474
Zusätzliche Namen:: PYD and CARD domain containing , ASC , CARD5 , TMS , TMS-1 , TMS1
Anwendung:: WB, IHC-P, IHC-Fr, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human TMS1. The exact sequence is proprietary.
Klon:: N1C3
Uniprot:: Q9ULZ3
Synonyme:: apoptosis-associated speck-like protein containing a CARD;ASC;CARD5;caspase recruitment domain-containing protein 5;PYD and CARD domain-containing protein;target of methylation-induced silencing 1;TMS;TMS-1;TMS1
Weitere Details:: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Versandbedingungen:: Blue Ice