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  2. Polyclonal

GTX102453

BMPR1B antibody [N3C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX102453
Zusätzliche Namen:
bone morphogenetic protein receptor type 1B , ALK-6 , ALK6 , AMDD , BDA1D , BDA2 , CDw293
Anwendung:
WB, IHC-P, IHC-Fr
Konzentration:
0.1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Bovine, Human, Mouse, Rat
Buffer:
PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:
Recombinant protein encompassing a sequence within the Intracellular domain of human BMPR1B. The exact sequence is proprietary.
Klon:
N3C3
Uniprot:
O00238
Synonyme:
activin receptor-like kinase 6;ALK-6;ALK6;AMDD;BDA1D;BDA2;BMP type-1B receptor;BMPR-1B;bone morphogenetic protein receptor type-1B;bone morphogenetic protein receptor, type IB;CDw293;serine/threonine receptor kinase
Weitere Details:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. [provided by RefSeq]
Versandbedingungen:
Blue Ice