GTX102406
BAG2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX102406
- Zusätzliche Namen:
- BCL2 associated athanogene 2 , BAG-2 , dJ417I1.2
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human BAG2. The exact sequence is proprietary.
- Uniprot:
- O95816
- Synonyme:
- BAG family molecular chaperone regulator 2;BAG-2;bcl-2-associated athanogene 2;BCL2 associated athanogene 2;dJ417I1.2;dJ417I1.2 (BAG-family molecular chaperone regulator 2)
- Weitere Details:
- BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice