GTX102051
PUF60 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX102051
- Zusätzliche Namen:
- poly(U) binding splicing factor 60 , FIR , RoBPI , SIAHBP1 , VRJS
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 0.75 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human PUF60. The exact sequence is proprietary.
- Uniprot:
- Q9UHX1
- Synonyme:
- 60 kDa poly(U)-binding-splicing factor;FBP interacting repressor;FIR;FUSE-binding protein-interacting repressor;poly(U) binding splicing factor 60KDa;poly(U)-binding-splicing factor PUF60;pyrimidine tract binding splicing factor;Ro ribonucleoprotein-binding protein 1;Ro-binding protein 1;RoBPI;Siah binding protein 1;Siah-binding protein 1;SIAHBP1;VRJS
- Weitere Details:
- The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice