GTX101710
DAP5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX101710
- Zusätzliche Namen:
- eukaryotic translation initiation factor 4 gamma 2 , AAG1 , DAP5 , NAT1 , P97
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human DAP5. The exact sequence is proprietary.
- Uniprot:
- P78344
- Synonyme:
- AAG1;aging-associated protein 1;DAP-5;DAP5;death-associated protein 5;eIF-4-gamma 2;eIF-4G 2;eIF4G 2;eukaryotic translation initiation factor 4 gamma 2;eukaryotic translation initiation factor 4G-like 1;NAT1;P97
- Weitere Details:
- Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice