GTX101160
MLH1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX101160
- Zusätzliche Namen:
- mutL homolog 1 , COCA2 , FCC2 , HNPCC , HNPCC2 , hMLH1
- Anwendung:
- WB, IF, ICC
- Konzentration:
- 0.94 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human MLH1. The exact sequence is proprietary.
- Uniprot:
- P40692
- Synonyme:
- COCA2;DNA mismatch repair protein Mlh1;FCC2;hMLH1;HNPCC;HNPCC2;MMRCS1;mutL homolog 1, colon cancer, nonpolyposis type 2;MutL protein homolog 1
- Weitere Details:
- This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice