POR antibody [N2C2], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX101100
Zusätzliche Namen:: cytochrome p450 oxidoreductase , CPR , CYPOR , P450R
Anwendung:: WB, IHC-P
Konzentration:: 0.75 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human POR. The exact sequence is proprietary.
Klon:: N2C2
Uniprot:: P16435
Synonyme:: CPR;CYPOR;NADPH--cytochrome P450 reductase;NADPH--hemoprotein reductase;NADPH-dependent cytochrome P450 reductase;P450 (cytochrome) oxidoreductase;P450R
Weitere Details:: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq]