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  2. Polyclonal

GTX100913

B-Raf antibody [N2C1], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX100913
Zusätzliche Namen:
B-Raf proto-oncogene, serine/threonine kinase , B-RAF1 , B-raf , BRAF1 , NS7 , RAFB1
Anwendung:
WB, IHC-P, IP
Konzentration:
0.21 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human B-Raf. The exact sequence is proprietary.
Klon:
N2C1
Uniprot:
P15056
Synonyme:
94 kDa B-raf protein;B-raf;B-Raf proto-oncogene serine/threonine-protein kinase (p94);B-Raf serine/threonine-protein;B-RAF1;BRAF1;murine sarcoma viral (v-raf) oncogene homolog B1;NS7;p94;proto-oncogene B-Raf;RAFB1;serine/threonine-protein kinase B-raf;v-raf murine sarcoma viral oncogene homolog B;v-raf murine sarcoma viral oncogene homolog B1
Weitere Details:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq]
Versandbedingungen:
Blue Ice