CRK antibody [N2C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX100901
Zusätzliche Namen:: CRK proto-oncogene, adaptor protein , CRKII , p38
Anwendung:: WB, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 40% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human CRK. The exact sequence is proprietary.
Klon:: N2C3
Uniprot:: P46108
Synonyme:: adapter molecule crk;CRKII;p38;proto-oncogene c-Crk;v-crk avian sarcoma virus CT10 oncogene homolog;v-crk sarcoma virus CT10 oncogene-like protein
Weitere Details:: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq]

Versandbedingungen:: Blue Ice