LYRIC antibody [N2C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX100587
Zusätzliche Namen:: metadherin , 3D3 , AEG-1 , AEG1 , LYRIC , LYRIC/3D3
Anwendung:: WB, IHC-P, IF, ICC
Konzentration:: 0.69 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human LYRIC . The exact sequence is proprietary.
Klon:: N2C3
Uniprot:: Q86UE4
Synonyme:: 3D3;3D3/LYRIC;AEG-1;AEG1;astrocyte elevated gene 1;astrocyte elevated gene-1 protein;LYRIC;LYRIC/3D3;lysine-rich CEACAM1 co-isolated protein;Metadherin;metastasis adhesion protein;protein LYRIC
Weitere Details:: Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.