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  2. Polyclonal

GTX100459

MUC1 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX100459
Zusätzliche Namen:
mucin 1, cell surface associated , ADMCKD , ADMCKD1 , CA 15-3 , CD227 , EMA , H23AG , KL-6 , MAM6 , MCD , MCKD , MCKD1 , MUC-1 , MUC-1/SEC , MUC-1/X , MUC1/ZD , PEM , PEMT , PUM
Anwendung:
WB, IHC-P, IF, ICC, IP
Konzentration:
0.35 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:
Recombinant protein encompassing a sequence within the Extracellular domain of human MUC1. The exact sequence is proprietary.
Uniprot:
P15941
Synonyme:
ADMCKD;ADMCKD1;ADTKD2;breast carcinoma-associated antigen DF3;CA 15-3;cancer antigen 15-3;carcinoma-associated mucin;CD227;EMA;episialin;H23 antigen;H23AG;KL-6;krebs von den Lungen-6;MAM6;MCD;MCKD;MCKD1;MUC-1;MUC-1/SEC;MUC-1/X;MUC1/ZD;mucin 1, transmembrane;mucin-1;peanut-reactive urinary mucin;PEM;PEMT;polymorphic epithelial mucin;PUM;tumor associated epithelial mucin;tumor-associated epithelial membrane antigen;Tumor-associated mucin
Weitere Details:
This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq]
Versandbedingungen:
Blue Ice