GTX100436
ABCG2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX100436
- Zusätzliche Namen:
- ATP binding cassette subfamily G member 2 (Junior blood group) , ABC15 , ABCP , BCRP , BCRP1 , BMDP , CD338 , CDw338 , EST157481 , GOUT1 , MRX , MXR , MXR-1 , MXR1 , UAQTL1
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the Intracellular domain of human ABCG2. The exact sequence is proprietary.
- Uniprot:
- Q9UNQ0
- Synonyme:
- ABC transporter;ABC15;ABCP;ATP-binding cassette transporter G2;ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group);BCRP;BCRP1;BMDP;breast cancer resistance protein;broad substrate specificity ATP-binding cassette transporter ABCG2;CD338;CDw338;EST157481;GOUT1;mitoxantrone resistance-associated protein;MRX;multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2;MXR;MXR-1;MXR1;placenta specific MDR protein;placenta-specific ATP-binding cassette transporter;UAQTL1;urate exporter
- Weitere Details:
- The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice