GTX100245
Calcipressin 1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX100245
- Zusätzliche Namen:
- regulator of calcineurin 1 , ADAPT78 , CSP1 , DSC1 , DSCR1 , MCIP1 , RCN1
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Calcipressin 1. The exact sequence is proprietary.
- Uniprot:
- P53805
- Synonyme:
- ADAPT78;calcipressin-1;calcium and oxidant-inducible mRNA;CSP1;Down syndrome candidate region 1;Down syndrome critical region gene 1;Down syndrome critical region protein 1;DSC1;DSCR1;MCIP1;modulatory calcineurin-interacting protein 1;myocyte-enriched calcineurin-interacting protein 1;near DSCR proline-rich protein;RCN1;Regulator of calcineurin 1
- Weitere Details:
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice