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  2. Polyclonal

GTX100202

Cav beta 4 antibody [C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX100202
Zusätzliche Namen:
calcium voltage-gated channel auxiliary subunit beta 4 , CAB4 , CACNLB4 , EA5 , EIG9 , EJM , EJM4 , EJM6
Anwendung:
WB, IHC-P, IHC-Fr, IF, ICC
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
PBS, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Cav beta 4. The exact sequence is proprietary.
Klon:
C3
Uniprot:
O00305
Synonyme:
CAB4;CACNLB4;calcium channel voltage-dependent subunit beta 4;dihydropyridine-sensitive L-type, calcium channel beta-4 subunit;EA5;EIG9;EJM;EJM4;EJM6;voltage-dependent L-type calcium channel subunit beta-4
Weitere Details:
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Versandbedingungen:
Blue Ice