GTX100130
DDB1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX100130
- Zusätzliche Namen:
- damage specific DNA binding protein 1 , DDBA , UV-DDB1 , XAP1 , XPCE , XPE , XPE-BF
- Anwendung:
- WB, IHC-P, IF, ICC, IP
- Konzentration:
- 0.34 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human DDB1. The exact sequence is proprietary.
- Uniprot:
- Q16531
- Synonyme:
- damage-specific DNA binding protein 1, 127kDa;Damage-specific DNA-binding protein 1;DDB p127 subunit;DDBA;DNA damage-binding protein 1;DNA damage-binding protein a;HBV X-associated protein 1;UV-damaged DNA-binding factor;UV-damaged DNA-binding protein 1;UV-DDB 1;UV-DDB1;WHIKERS;XAP-1;XAP1;xeroderma pigmentosum group E-complementing protein;XPCE;XPE;XPE-BF;XPE-binding factor
- Weitere Details:
- This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice