GTX05209
FBXO32 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX05209
- Zusätzliche Namen:
- FBXO32,Fbox protein 32,Fbx32,MAFbx,Atrogin 1,MafBx,F-box protein 32
- Anwendung:
- ELISA, Flow Cytometry, WB, IF, ICC
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, no preservatives.
- Immunogen:
- E.coli-derived human FBXO32 recombinant protein (Position: Q6-F355)
- Uniprot:
- Q969P5
- Synonyme:
- atrogin 1;Atrogin-1;F-box only protein 32;Fbx32;MAFbx;muscle atrophy F-box protein
- Weitere Details:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
- Versandbedingungen:
- Blue Ice