GTX04991
5-HT2C receptor antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX04991
- Zusätzliche Namen:
- HTR1C,HTR2C,Serotonin receptor 2C,SR-2C,5HT1C,5HT2C,5HTR2C,5hydroxytryptamine receptor 2C,5HT2C Receptor,5-HT2C receptor,5-hydroxytryptamine receptor 2C
- Anwendung:
- WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 150mM NaCl, 50%Glycerol, 0.02% Sodium Azide.
- Immunogen:
- A synthesized peptide derived from human HTR2C(Accession P28335), corresponding to amino acid residues K170-F220.
- Uniprot:
- P28335
- Synonyme:
- 5-HT1C;5-HT2C;5-HTR2C;5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled;5-hydroxytryptamine receptor 1C;5-hydroxytryptamine receptor 2C;5HTR2C;HTR1C;serotonin 5-HT-1C receptor;serotonin 5-HT-2C receptor;Serotonin receptor 2C
- Weitere Details:
- This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]
- Versandbedingungen:
- Blue Ice