GTX04911
xCT / SLC7A11 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX04911
- Zusätzliche Namen:
- CCBR1,SLC7A11,solute carrier family 7 member 11,xCT
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium Azide.
- Immunogen:
- A synthesized peptide derived from human SLC7A11(Accession Q9UPY5), corresponding to amino acid residues T195-A245.
- Uniprot:
- Q9UPY5
- Synonyme:
- amino acid transport system xc-;calcium channel blocker resistance protein CCBR1;CCBR1;cystine/glutamate transporter;solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11;Solute carrier family 7 member 11;solute carrier family 7, (cationic amino acid transporter, y+ system) member 11;xCT
- Weitere Details:
- This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
- Versandbedingungen:
- Blue Ice