NKX2.8 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX04864
Zusätzliche Namen:: NK2 homeobox 8,NKX2.8,NKX28,NKX2H,Nkx29
Anwendung:: WB
Konzentration:: 0.5 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 2% Sucrose, 0.09% Sodium Azide.
Immunogen:: A synthetic peptide directed towards the C terminal region of human NKX2-8
Uniprot:: O15522
Synonyme:: homeobox protein NK-2 homolog H;homeobox protein Nkx-2.8;NK-2 homolog 8;NK-2 homolog H;NK2 transcription factor related, locus 8;Nkx2-9;NKX2.8;NKX2H
Weitere Details:: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015]