GTX04615
SLC26A5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX04615
- Zusätzliche Namen:
- solute carrier family 26 member 5 , DFNB61 , PRES
- Anwendung:
- WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.
- Immunogen:
- A synthesized peptide derived from human SLC26A5(Accession P58743), corresponding to amino acid residues A427-V477.
- Uniprot:
- P58743
- Synonyme:
- DFNB61;PRES;prestin;prestin (motor protein);solute carrier family 26 (anion exchanger), member 5;Solute carrier family 26 member 5
- Weitere Details:
- This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
- Versandbedingungen:
- Blue Ice