Claudin 18.2 antibody [ARC5062-02]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX04575
Zusätzliche Namen:: claudin 18 , SFTA5 , SFTPJ
Anwendung:: IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 50% Glycerol, 0.05% proclin300.
Immunogen:: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CLDN18.2 (P56856-2).
Klon:: ARC5062-02
Uniprot:: P56856
Synonyme:: claudin-18;SFTA5;SFTPJ;surfactant associated 5;surfactant associated protein J;surfactant, pulmonary associated protein J
Weitere Details:: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]

Versandbedingungen:: Blue Ice