GTX04545
CYP7B1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX04545
- Zusätzliche Namen:
- cytochrome P450 family 7 subfamily B member 1 , CBAS3 , CP7B , SPG5A
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.05% proclin300.
- Immunogen:
- A synthesized peptide derived from human CYP7B1 (NP_004811.1), corresponding to amino acid residues V200-T300.
- Uniprot:
- O75881
- Synonyme:
- 24-hydroxycholesterol 7-alpha-hydroxylase;25-hydroxycholesterol 7-alpha-hydroxylase;25/26-hydroxycholesterol 7-alpha-hydroxylase;3-hydroxysteroid 7-alpha hydroxylase;CBAS3;CP7B;cytochrome P450 7B1;cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1;oxysterol 7-alpha-hydroxylase;SPG5A
- Weitere Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
- Versandbedingungen:
- Blue Ice