GTX04506
Dectin-1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX04506
- Zusätzliche Namen:
- C-type lectin domain family 7, member a , BGR , Clecsf12 , beta-GR
- Anwendung:
- ELISA, Flow Cytometry, WB, IHC-P
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, no preservatives.
- Immunogen:
- E.coli-derived mouse Dectin-1/Clec7a recombinant protein (Position: Q17-L244)
- Synonyme:
- beta-;beta-glucan receptor;beta-GR;BG;BGR;C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12;C-type lectin domain family 7 member A;C-type lectin superfamily member 12;Clecsf;Clecsf12;DC-associated C-type lectin 1;dectin;dectin-1;dendritic cell-associated C-type lectin 1
- Weitere Details:
- Enables (1->3)-beta-D-glucan binding activity; (1->3)-beta-D-glucan immune receptor activity; and opsonin binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of intracellular signal transduction; and response to fungus. Acts upstream of or within several processes, including phagocytosis; positive regulation of tumor necrosis factor production; and regulation of calcineurin-NFAT signaling cascade. Located in external side of plasma membrane. Is expressed in several structures, including gut; limb; musculature; spleen; and ventral grey horn. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Orthologous to human CLEC7A (C-type lectin domain containing 7A). [provided by Alliance of Genome Resources, Jul 2025]
- Versandbedingungen:
- Blue Ice