STING antibody [MSVA-515M] HistoMAX[TM]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX04484
Zusätzliche Namen:: transmembrane protein 173 , ERIS , MITA , MPYS , NET23 , SAVI , STING , STING-beta , hMITA , hSTING
Anwendung:: IHC-P
Konzentration:: 0.2 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% sodium azide.
Immunogen:: Recombinant fragment (around aa190-290) of human TMEM173 protein
Klon:: MSVA-515M
Uniprot:: Q86WV6
Synonyme:: endoplasmic reticulum IFN stimulator;endoplasmic reticulum interferon stimulator;ERIS;hMITA;hSTING;Mediator of IRF3 activation;MITA;mitochondrial mediator of IRF3 activation;MPYS;N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner;NET23;SAVI;stimulator of interferon genes protein;stimulator of interferon protein;STING;STING-beta;TMEM173;transmembrane protein 173
Weitere Details:: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Versandbedingungen:: Blue Ice