MCM3 antibody [MSVA-503M] HistoMAX[TM]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX04424
Zusätzliche Namen:: minichromosome maintenance complex component 3 , HCC5 , P1-MCM3 , P1.h , RLFB
Anwendung:: IHC-P
Konzentration:: 0.2 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% sodium azide.
Immunogen:: Recombinant human MCM3 fragment
Klon:: MSVA-503M
Uniprot:: P25205
Synonyme:: cervical cancer proto-oncogene 5;DNA polymerase alpha holoenzyme-associated protein P1;DNA replication factor MCM3;DNA replication licensing factor MCM3;HCC5;hRlf beta subunit;MCM3 minichromosome maintenance deficient 3;minichromosome maintenance deficient 3;P1-MCM3;P1.h;p102;replication licensing factor, beta subunit;RLF subunit beta;RLFB
Weitere Details:: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018]

Versandbedingungen:: Blue Ice