GTX04257
AIRE antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX04257
- Zusätzliche Namen:
- autoimmune regulator , AIRE1 , APECED , APS1 , APSI , PGA1
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 2% sucrose, 0.09% sodium azide.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human AIRE.
- Uniprot:
- O43918
- Synonyme:
- AIRE1;APECED;APS1;APSI;autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein;autoimmune regulator;PGA1
- Weitere Details:
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- Versandbedingungen:
- Blue Ice