USP2 antibody [1738CT331.50.87]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX03924
Zusätzliche Namen:: ubiquitin specific peptidase 2 , UBP41 , USP9
Anwendung:: WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.09% sodium azide.
Immunogen:: Recombinant protein between 1-258 amino acids from human USP2.
Klon:: 1738CT331.50.87
Uniprot:: O75604
Synonyme:: 41 kDa ubiquitin-specific protease;deubiquitinating enzyme 2;ubiquitin carboxyl-terminal hydrolase 2;ubiquitin specific protease 12;ubiquitin specific protease 9;ubiquitin thioesterase 2;ubiquitin-specific-processing protease 2;UBP41;USP9
Weitere Details:: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Versandbedingungen:: Blue Ice