GTX03807
MLKL antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX03807
- Zusätzliche Namen:
- mixed lineage kinase domain-like , 9130019I15Rik
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.09% sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 444-472 amino acids from the C-terminal region of mouse Mlkl.
- Uniprot:
- Q9D2Y4
- Synonyme:
- 9130019I15Rik;mixed lineage kinase domain-like protein
- Weitere Details:
- This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
- Versandbedingungen:
- Blue Ice