GTX03451
gp340 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX03451
- Zusätzliche Namen:
- deleted in malignant brain tumors 1 , GP340 , SAG , SALSA , muclin
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.
- Immunogen:
- A synthesized peptide derived from human DMBT1(Accession Q9UGM3), corresponding to amino acid residues P2370-G2398.
- Uniprot:
- Q9UGM3
- Synonyme:
- deleted in malignant brain tumors 1 protein;glycoprotein 340;GP340;hensin;muclin;SAG;salivary agglutinin;salivary scavenger and agglutinin;SALSA;surfactant pulmonary-associated D-binding protein;vomeroglandin
- Weitere Details:
- Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016]
- Versandbedingungen:
- Blue Ice