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GTX03321

BCL6 antibody [PG-B6]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX03321
Zusätzliche Namen:
BCL6 transcription repressor , BCL5 , BCL6A , LAZ3 , ZBTB27 , ZNF51
Anwendung:
IHC-P
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Unpurified
Lagerbedingungen:
2-8[o]C
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:
Recombinant BCL6 protein corresponding to amino acids 3-484 of the human BCL6 protein
Klon:
PG-B6
Uniprot:
P41182
Synonyme:
B cell CLL/lymphoma 6;B-cell lymphoma 5 protein;B-cell lymphoma 6 protein;B-cell lymphoma 6 protein transcript;BCL-5;BCL-6;BCL5;BCL6A;cys-his2 zinc finger transcription factor;LAZ3;lymphoma-associated zinc finger gene on chromosome 3;protein LAZ-3;ZBTB27;zinc finger and BTB domain-containing protein 27;zinc finger protein 51;zinc finger transcription factor BCL6S;ZNF51
Weitere Details:
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Versandbedingungen:
Blue Ice