PRAME antibody [EPR20330]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX03315
Zusätzliche Namen:: preferentially expressed antigen in melanoma , CT130 , MAPE , OIP-4 , OIP4
Anwendung:: IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.1% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant fragment within Human PRAME aa 100 to the C-terminus. The exact sequence is proprietary.
Klon:: EPR20330
Uniprot:: P78395
Synonyme:: cancer/testis antigen 130;CT130;MAPE;melanoma antigen preferentially expressed in tumors;OIP-4;OIP4;opa-interacting protein 4;Opa-interacting protein OIP4;preferentially expressed antigen in melanoma;preferentially expressed antigen of melanoma
Weitere Details:: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]