IL13 ELISA pair [IL13-I/IL13-3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX03077
Zusätzliche Namen:: interleukin 13 , IL-13 , P600
Anwendung:: ELISA
Physischer Zustand:: Liquid
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Reaktivitäten:: Human
Immunogen:: interleukin 13
Klon:: IL13-I/IL13-3
Uniprot:: P35225
Synonyme:: IL-13;interleukin-13;P600
Weitere Details:: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]