IL10 ELISA pair [MT60/51E6]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX03070
Zusätzliche Namen:: interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF
Anwendung:: ELISA
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Mouse
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Reaktivitäten:: Mouse
Immunogen:: interleukin 10
Klon:: MT60/51E6
Uniprot:: P22301
Synonyme:: CSIF;cytokine synthesis inhibitory factor;GVHDS;IL-10;IL10A;interleukin-10;T-cell growth inhibitory factor;TGIF
Weitere Details:: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]