TFPI antibody [GT1246]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02843
Zusätzliche Namen:: tissue factor pathway inhibitor , EPI , LACI , TFI , TFPI1
Anwendung:: WB
Konzentration:: 0.71 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles., -20[o]C 50% glycerol. Aliquot. Avoid freeze/thaw cycles.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: A synthesized peptide derived from human TFPI
Klon:: GT1246
Uniprot:: P10646
Synonyme:: anti-convertin;EPI;extrinsic pathway inhibitor;LACI;Lipoprotein-associated coagulation inhibitor;TFI;TFPI1;tissue factor pathway inhibitor;tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Weitere Details:: This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]

Versandbedingungen:: Blue Ice