FHIT antibody [GT1240]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02837
Zusätzliche Namen:: fragile histidine triad , AP3Aase , FRA3B
Anwendung:: WB
Konzentration:: 1.59 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles., -20[o]C 50% glycerol. Aliquot. Avoid freeze/thaw cycles.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Rat
Buffer:: PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: A synthesized peptide derived from human FHIT
Klon:: GT1240
Uniprot:: P49789
Synonyme:: AP3A hydrolase;AP3Aase;bis(5'-adenosyl)-triphosphatase;diadenosine 5',5'''-P1,P3-triphosphate hydrolase;dinucleosidetriphosphatase;FRA3B;Fragile histidine triad protein
Weitere Details:: The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]