Insulin antibody [GT1229]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02826
Zusätzliche Namen:: insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
Anwendung:: WB, IHC-P
Konzentration:: 0.61 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human, Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles., -20[o]C 50% glycerol. Aliquot. Avoid freeze/thaw cycles.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Buffer:: PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: A synthesized peptide derived from human Insulin
Klon:: GT1229
Uniprot:: P01308
Synonyme:: IDDM;IDDM1;IDDM2;ILPR;insulin;IRDN;MODY10;PNDM4;preproinsulin;proinsulin
Weitere Details:: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]