GTX02777
BAG3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX02777
- Zusätzliche Namen:
- BCL2 associated athanogene 3 , BAG-3 , BIS , CAIR-1 , MFM6
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 380-575 of human BAG3 (NP_004272.2).
- Uniprot:
- O95817
- Synonyme:
- BAG family molecular chaperone regulator 3;BAG-3;Bcl-2-associated athanogene 3;bcl-2-binding protein Bis;Bcl-2-binding protein BIS transcript 2;BCL2 associated athanogene 3;BCL2-binding athanogene 3;BIS;CAIR-1;docking protein CAIR-1;MFM6
- Weitere Details:
- BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice