TPO antibody [TPO/3813R]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02732
Zusätzliche Namen:: thyroid peroxidase , MSA , TDH2A , TPX
Anwendung:: IHC-P
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant fragment of human TPO (around aa 685-804)
Klon:: TPO/3813R
Uniprot:: P07202
Synonyme:: MSA;TDH2A;thyroid microsomal antigen;thyroid peroxidase;thyroperoxidase;TPX
Weitere Details:: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]