TIMP2 antibody [TIMP2/2488R]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02722
Zusätzliche Namen:: TIMP metallopeptidase inhibitor 2 , CSC-21K , DDC8
Anwendung:: IHC-P
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Bovine, Fish, Human, Mouse, Rabbit, Rat, Guinea Pig
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)
Klon:: TIMP2/2488R
Uniprot:: P16035
Synonyme:: CSC-21K;DDC8;metalloproteinase inhibitor 2;testicular secretory protein Li 57;tissue inhibitor of metalloproteinases 2
Weitere Details:: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]