SPTBN2 antibody [SPTBN2/2894R]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02716
Zusätzliche Namen:: spectrin beta, non-erythrocytic 2 , GTRAP41 , SCA5 , SCAR14
Anwendung:: ELISA, Flow Cytometry, WB, IHC-P
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant human SPTBN2 fragment (aa356-475)
Klon:: SPTBN2/2894R
Uniprot:: O15020
Synonyme:: beta-III spectrin;glutamate transporter EAAT4-associated protein 41;GTRAP41;SCA5;SCAR14;spectrin beta chain, brain 2;spectrin beta chain, non-erythrocytic 2;spectrin beta III sigma 2;spectrin, non-erythroid beta chain 2;spinocerebellar ataxia 5 protein
Weitere Details:: Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]

Versandbedingungen:: Blue Ice