Myosin Heavy Chain 11 antibody [MYH11/2303R]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02683
Zusätzliche Namen:: myosin heavy chain 11 , AAT4 , FAA4 , SMHC , SMMHC
Anwendung:: IHC-P
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Bovine, Canine, Human, Porcine, Rabbit, Rat, Feline, Guinea Pig
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant full-length human MYH11 protein
Klon:: MYH11/2303R
Uniprot:: P35749
Synonyme:: AAT4;epididymis secretory sperm binding protein;FAA4;Myosin heavy chain 11;Myosin heavy chain, smooth muscle isoform;myosin-11;myosin, heavy chain 11, smooth muscle;myosin, heavy polypeptide 11, smooth muscle;SMHC;SMMHC;VSCM2
Weitere Details:: The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice