Cytokeratin 8 antibody [KRT8/4067R]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02668
Zusätzliche Namen:: keratin 8 , CARD2 , CK-8 , CK8 , CYK8 , K2C8 , K8 , KO
Anwendung:: Flow Cytometry, WB, IHC-P, IF, ICC
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Keratin preparation from a human carcinoma. An epitope of this antibody is located between aa343-357.
Klon:: KRT8/4067R
Uniprot:: P05787
Synonyme:: CARD2;CK-8;CK8;CYK8;cytokeratin-8;K2C8;K8;keratin 8, type II;Keratin-8;keratin, type II cytoskeletal 8;KO;type-II keratin Kb8
Weitere Details:: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]