BCL10 antibody [BL10/2988R]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX02597
Zusätzliche Namen:: BCL10 immune signaling adaptor , CARMEN , CIPER , CLAP , IMD37 , c-E10 , mE10
Anwendung:: Flow Cytometry, IHC-P, IF, ICC
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: protein a/g purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant human BCL10 protein fragment (around aa122-168)
Klon:: BL10/2988R
Uniprot:: O95999
Synonyme:: B cell CLL/lymphoma 10;B-cell CLL/lymphoma 10;B-cell lymphoma/leukemia 10;c-E10;CARD containing molecule enhancing NF-kB;CARD-containing apoptotic signaling protein;CARD-containing molecule enhancing NF-kappa-B;CARD-containing proapoptotic protein;CARD-like apoptotic protein;CARMEN;caspase-recruiting domain-containing protein;cCARMEN;CED-3/ICH-1 prodomain homologous E10-like regulator;cellular homolog of vCARMEN;cellular-E10;CIPER;CLAP;hCLAP;IMD37;mammalian CARD-containing adapter molecule E10;mE10
Weitere Details:: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Versandbedingungen:: Blue Ice