IRF4 / MUM1 antibody [EAU32]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX01894
Zusätzliche Namen:: interferon regulatory factor 4 , LSIRF , MUM1 , NF-EM5 , SHEP8
Anwendung:: IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: 2-8[o]C Do not freeze.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: Prokaryotic recombinant protein corresponding to 313 amino acids of the human multiple myeloma oncogene 1 (MUM-1) molecule.
Klon:: EAU32
Uniprot:: Q15306
Synonyme:: interferon regulatory factor 4;LSIRF;lymphocyte-specific interferon regulatory factor;multiple myeloma oncogene 1;MUM1;NF-EM5;SHEP8
Weitere Details:: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]