GTX01835
TdT antibody [ZM51]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX01835
- Zusätzliche Namen:
- DNA nucleotidylexotransferase , TDT
- Anwendung:
- IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Purified
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Tris-HCl, 0.2% BSA, 0.09% Sodium azide.
- Immunogen:
- Recombinant fragment (around aa 52-192) of human DNTT protein
- Klon:
- ZM51
- Uniprot:
- P04053
- Synonyme:
- DNA nucleotidylexotransferase;nucleosidetriphosphate:DNA deoxynucleotidylexotransferase;TDT;terminal addition enzyme;terminal deoxynucleotidyltransferase;terminal deoxyribonucleotidyltransferase;terminal transferase
- Weitere Details:
- This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice