GTX01614
CD163 antibody [ZM29]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX01614
- Zusätzliche Namen:
- CD163 molecule , M130 , MM130 , SCARI1
- Anwendung:
- IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Purified
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Tris-HCl, 0.2% BSA, 0.09% Sodium azide.
- Immunogen:
- Recombinant human CD163 fragment (around aa 43-196)
- Klon:
- ZM29
- Uniprot:
- Q86VB7
- Synonyme:
- hemoglobin scavenger receptor;M130;macrophage-associated antigen;MM130;SCARI1;scavenger receptor cysteine-rich type 1 protein M130
- Weitere Details:
- The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- Versandbedingungen:
- Blue Ice