CD45 antibody [2D1] (PE)

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX01462-08
Zusätzliche Namen:: protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , LCA , LY5 , PTPRC , T200 , protein tyrosine phosphatase, receptor type C , CD45.1 , CD45.2 , CD45RA , CD45RB , CD45RC
Anwendung:: Flow Cytometry
Konzentration:: 0.1 mg/ml
Physischer Zustand:: Liquid
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Rabbit
Buffer:: 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Immunogen:: protein tyrosine phosphatase receptor type C
Klon:: 2D1
Uniprot:: P08575
Synonyme:: B220;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;LY5;protein tyrosine phosphatase, receptor type, c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen
Weitere Details:: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Versandbedingungen:: Blue Ice